HOT SALE Ivabradine Hydrochloride CAS 148849-67-6
Product Description
SPECIFICATION
PRODUCT NAME: hot SALE Ivabradine Hydrochloride CAS 148849-67-6
CAS NO: <Span style="line-height: normal;">148849-67-6
USAGE: Ivabradine Hydrochloride, also known as S-16257, is the hydrochloride salt preparation of Ivabradine, a bradycardic agent. Studies have shown that Ivabradine inhibits T cell migration and causes a decrease of chemokine-induced PI-3 kinase activity. Exposure of rabbit sinoatrial node cells to Ivabradine has been reported to cause a blockade of the hyperpolarization-activated I(f) current without resulting in a shift of the voltage range of the activation curve.
SPECIFICATION AS FOLLOWS.
Product Name: IVABRADINE HCl
Cas no.:148849-67-6
Batch No.: 110102
Mfg. Date: Jan 26.,2011
Rep. Date: Feb 23.,2011
Exp. Date: Jan 25.,2013
Quantity: 606G
Items | Standards | Results |
Appearance | White to off-white crystalline powder | White crystalline powder |
Solubility | Very soluble in methanol, free soluble in ethanol, soluble in water, Sparingly soluble in 0.1M HCl solution and in soluble in ether | Complies |
Specific Rotation (on dried basis, 1% solution in DMSO) | +6.0°~ +9.0° | +8.73° |
Identification | HPLC/UV | Complies |
Related Substances | Total ≤1.0% Maximum single impurity ≤0.5% | 0.15% 0.10% |
Optical Isomer | NMT 0.5% | 0 |
| Loss on drying (Dry it at 105℃ in an electric air blowing dryer till a constant weight) | NMT 1.0% | 0.29% |
Residue on ignition | NMT 0.1% | 0.05% |
Heavy metals | NMT 20ppm | < 20ppm |
Assay | NLT 98.5% | 99.82% |
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Product Categories : Fluorinated Silicone Rubber
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